Unfortunately, no. Of course, you are free to make donations to whomever you choose, but the tax law limits deductible contributions to those made to 501(3)(c) organizations. Explore the organizations benefiting individuals impacted by the disaster you’re concerned about so you can decide whether to make donations to these organizations. Watch out for fake organizations purporting to help victims. Check the organization’s tax exempt status through the IRS’ Exempt Organization Select Check tool. Check the charity’s rating at Charity Navigator.
Interest on debt used to carry investments, but not including interest expense from a passive activity. Deductions are limited to net investment income.